Christophe Trefois
Head of Technology | Luxembourg National Data Service
Leading technology innovation and AI infrastructure development for Luxembourg's national data ecosystem. Expert in large-scale data infrastructure, genomic data federation, and building GDPR-compliant platforms with a focus on enabling cutting-edge research and innovation.
Current Role
Head of Technology, LNDS Luxembourg
Since November 2022
Leading the technology team at Luxembourg National Data Service, I oversee the design, development, and operation of data infrastructure that enables secure secondary use of public sector data. Our work focuses on building trustable platforms for data sharing, implementing FAIR data principles, and supporting Luxembourg's digital transformation strategy.
Key responsibilities include:
- Leading a multidisciplinary team of data, software, DevOps, security, and infrastructure engineers
- Architecting secure processing environments and federated data access platforms
- Overseeing development of data services including cataloguing, pseudonymization, and synthetic data generation
- Contributing to European data space initiatives and the European Health Data Space
- Establishing partnerships with organizations like DFKI for AI collaboration and ERTICO for smart mobility
- Ensuring data protection by design and GDPR compliance across all technical solutions
Expertise & Focus Areas
🤖 AI Infrastructure
Leading Luxembourg's AI Factory initiative to democratize access to artificial intelligence capabilities for research and industry.
🧬 Genomic Data Infrastructure
Leading WP4 of the European GDI project, building federated infrastructure for secure genomic data access across 24 countries.
💻 Data Platforms
Building scalable, GDPR-compliant platforms for biomedical data analysis, storage, and sharing across institutions.
🔒 Data Governance
Expertise in data protection, consent management, and building compliant research data infrastructure (DAISY project).
🔄 Reproducible Research
Developing tools and frameworks for ensuring reproducibility in computational research and data science.
🤝 Open Science
Promoting FAIR data principles, open access, and transparent research practices through European initiatives.
Career Highlights
2014 - 2022: Luxembourg Centre for Systems Biomedicine (LCSB)
Bioinformatics Core Group
- Led bioinformatics infrastructure development
- Deputy Technical Coordinator of ELIXIR Luxembourg (2017-2022)
- Developed GDPR-compliant data management systems
- Coordinated multi-institutional research projects
2010 - 2014: PhD in Systems Biology
LCSB, University of Luxembourg
- Research on Parkinson's disease molecular mechanisms
- Developed computational models for disease progression
- Visiting researcher at Institute for Systems Biology, Seattle
2008 - 2010: Ernst & Young Luxembourg
IT Consultant & IT Auditor
- IT consulting for financial and industrial sectors
- IT security and compliance auditing
2008: MSc in Communication Systems
EPFL (Swiss Federal Institute of Technology Lausanne)
- Master thesis at SAP Labs France on wireless sensor networks security
- Focus on distributed systems and network security
Key Projects & Initiatives
Luxembourg AI Factory
Principal Investigator leading Luxembourg's national AI infrastructure to accelerate AI adoption across research and industry sectors.
GDI Project (WP4 Leader)
Leading Work Package 4 of the €40M European Genomic Data Infrastructure project, creating federated access to genomic data.
ELIXIR Luxembourg
Former Deputy Technical Coordinator contributing to Europe's life science data infrastructure and sustainable data management.
DAISY Platform
Developed comprehensive GDPR-compliant data management system for biomedical research, enabling accountability and transparency.
Recognition & Service
- Mendeley Advisor (since 2011) - Supporting researchers in reference management
- Program Committee Member - Multiple international conferences (DILS 2017, ICT Innovations 2018-2019, ICT 2019)
- Invited Speaker - Conferences on bioinformatics, data management, and reproducible research
- Workshop Organizer - Big Data & Medicine, GDPR compliance, standardization in life sciences